The content on this page is intended to healthcare professionals and equivalents.
Developed in collaboration with medical experts and surgeons, Synapse 3D clinical applications offer solutions that address the real needs of medical care. Combining advanced technologies and innovative analysis processes, the software ensures fast and accurate image processing, which is essential for reliable and safe clinical decisions. Studies highlight that the use of Synapse 3D increases patient safety and significantly increases the confidence*1 and efficacy of surgical procedures*2. The unified and intuitive interface between applications allows for a consistent and simplified experience, while the intelligent integration of up to five applications at the same time provides greater agility and efficiency in the workflow of healthcare professionals.
Synapse 3D goes beyond just being software; It is a tool for continuous innovation that redefines image analysis and enhances patient care, positively impacting clinical practice.
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4 Chambers Review It allows detailed visualization of the left and right ventricles, atria, and myocardial regions from multi-temporal phase CT images. The app calculates important cardiac function parameters, such as ventricular ejection fraction (EF), and makes it possible to monitor variations in ventricular and atrial volumes over time, providing comprehensive analysis.
Provides aid for transcatheter aortic valve replacement (TAVR) planning by providing detailed measurements of different aortic valve angles and accurate imaging of the cardiac and aortic regions. The software confirms the size of the aorta, assesses the presence of calcification, and determines the appropriate size and length of the catheter to be used, ensuring accurate and effective preparation for the procedure.
It provides essential mitral valve measurements and generates key results for transcatheter replacement planning (TMVR) from CT images. In addition, it calculates the volume of calcium and presents the location of the virtual valve, optimizing the preparation and execution of clinical procedures.
It offers a detailed analysis, providing an accurate assessment of the calcium load in the coronary arteries. It displays the calcified areas and volumes of the coronary arteries by color and calculates calcification quantitatively using the Agatston scoring method.
It generates detailed images of the left and right ventricles, atria, and myocardial regions from CT images with multiple temporal phases. The software allows the visualization of pulmonary veins, both in preoperative simulation for ablation and in postoperative observation, allowing an accurate analysis to support the planning and monitoring of the procedure.
It allows detailed analysis of cardiac function by visualizing the contours of the ventricle and myocardium from multi-phase CT images. The tool enables automatic or manual contour delineation and calculates essential parameters, such as ejection fraction (EF), end-diastolic volume (EDV), end-stroke volume (ESV), and stroke volume. This provides a complete and accurate assessment of the heart's performance, aiding diagnoses and clinical decisions.
Designed to analyze cardiac function from multi-time phase MR images. The software presents visualization of the contours of the ventricle and myocardium, allowing automatic or manual segmentation. Calculates and provides detailed metrics such as ejection fraction (EF), end-diastolic volume (EDV), end-stroke volume (ESV), and stroke volume, providing a comprehensive evaluation of performance throughout the cardiac cycle.
Provides visualization of cardiac anatomy fusion from CT or MRI images, with functional MR, CT or SPECT analyses. With an integrated and detailed view, it enables a more complete and accurate analysis of cardiac conditions through the fusion of different imaging modalities.
It analyzes myocardial blood flow using multiphase 3D cardiac imaging. The software calculates myocardial blood volume (MBV), myocardial blood flow (MBF), time to peak (TTP), peak enhancement (PE), and peak enhancement factor (PER), providing a detailed assessment of myocardial perfusion and cardiovascular health.
Creates detailed images and automatically identifies coronary arteries, performing analysis of stenosis measurements, plaque quantification, and virtual stents for procedure planning. The app allows easy adjustment of the automatically generated paths, offering an interface with multiple visualization options that adapt per user, providing flexibility and accuracy in diagnosis and clinical planning.
It offers the creation and detailed identification of coronary arteries, enabling accurate stenosis measurements and simulations of vascular prostheses. The tool offers simple adjustments to the automatically generated paths and a flexible interface with adaptive visualization options to meet the needs of each user, increasing diagnostic accuracy and facilitating clinical planning.
Designed to assess myocardial viability through delayed enhancement measurements, which include area and volume. The highlighted areas can be overlaid on general maps for more detailed analysis, and the short-axis view highlights aspects such as average intensity and the ratio of the inner to outer wall.
Ability to calculate both blood flow volume and flow velocity, based on a user-defined region of interest (ROI), to provide essential data on cardiovascular dynamics.
It uses 4D perfusion data to analyze changes in cerebral blood flow from dynamic CT images. Calculates cerebral blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT), and time to peak (TTP)
Uses perfusion data to assess changes in cerebral blood flow on dynamic CT images and calculates CBV, CBF, MTT and TTP.
Employs perfusion data to analyze changes in cerebral blood flow in dynamic MRI imaging and provides calculated parameters: CBV, CBF, MTT and TTP
It performs tensor analysis from diffusion-weighted MRI images and enables the extraction and visualization of white matter tractography paths. Additional images, mainly from CT, can be included to extract other regions such as skin, bones, brain parenchyma, tumors, and vessels to create craniotomy simulations.
It extracts blood vessels semi-automatically by subtraction and presents MIP projections, semi-transparent bones and distinction of vascular regions (arterial and venous).
It offers a detailed analysis of pulmonary nodules over time, as well as an assessment of the bronchi and areas of low attenuation in the lungs. Lung lobes extracted automatically or manually, allowing for personalized and accurate analysis.
It extracts lung (lung lobes), pulmonary artery, pulmonary vein, and bronchi and generates a 3D visualization of the extracted structures. The simulation of resection can be performed by segmentation by vascular and bronchial territories, with great precision, providing the pertinent volumes, making this tool essential for preoperative planning.
Identifies the three best paths that lead to lung injury. It creates a bronchoscopic simulation along these pathways, helping to visualize the entire path, for planning invasive exams in complex procedures.
Detects polyps, masses, cancers and other lesions in the colon through 3D analysis (navigation) with 2D image review.
Designed to create simulations of laparoscopic surgeries. It segments vessels, skin, bones, pancreas, spleen, and tumors, and simulates abdominal insufflation, port insertion, and targeting. It allows the performance of virtual resections of organs with relevant volumes.
It uses diffusion-weighted imaging to provide quantitative data on tissue microcapillary perfusion. Automatically displays maps such as ADC, eADC, D, D* and f, allowing selective placement of ROIs on areas of interest for detailed analysis.
It extracts the liver and nearby vessel regions from contrast-enhanced CT and MRI images, presenting the results as 3D masks for preoperative analysis. It allows simulations of hepatectomy and Couinaud segmentation on CT images for embolization planning.
Dedicated to liver function assessment, through contrast-enhanced multiphase MRI imaging and reference imaging. The results are presented and calculated for the liver and spleen regions.
It analyzes the blood flow of the abdominal organs, including the pancreas, over time. It calculates tissue blood volume (TBV), tissue blood flow (TBF), mean transit time (MTT), and time to peak (TTP).
Used to analyze tumors in the breast and generate a BI-RADS-based report. It has tools such as calculating kinetic contrast input and output curves, subtracting pre- and post-contrast images, and distance measurements of the nipple, skin, and chest wall. It also presents the volume of the tumor. It performs color overlays that can indicate phase highlighting and washout.
Combines CT images with SPECT or PET to visualize anatomical and functional data. Allows SUV evaluation in PET-CT studies, with comparative analysis of up to 10 exams.
It identifies and monitors changes in solid tumors over time, applying criteria such as PERCIST, RECIST, WHO, mRECIST, and Choi to the evaluation.
It analyzes tumors of the prostate gland, allowing measurements of diameter and volume. Its visualization tools include comparative observation of multiple image series (T2, ADC, DWI, DCE) and time intensity curves, with the possibility of generating reports based on PI-RADS.
It allows the extraction of kidney, renal cortex, renal vessels, sinus fat, and nearby organs from contrast-enhanced CT images, and generates a 3D visualization of the stretched structures. Nephrectomy simulation can be performed, assisting in surgical planning, with important information such as volumes.
It performs automatic extraction of the right and left kidneys from non-contrast CT images. The volumes are recorded for comparison with previous exams to monitor changes over time.
Possibility of merging 2D and 3D anatomical and functional images, allowing you to combine different modalities or exposures.
It simplifies the viewing of multimodality images in a single interface, and is also incorporated as a CD/DVD viewer.
Merges up to five series of images into the same space, displaying the volumetric rendering of the combined images. Ideal for planning complex surgical interventions such as fusion of CT and MRI images for tissue analysis.
Facilitates detailed analysis of CT, MRI, MN, and PT data, supporting analysis in different orthogonal, oblique, and endoscopic planes.
An application that provides virtual endoscopy tools for airways and contrasted vessels.
It allows the visualization of data sets side by side, optimizing comparative analysis and synchronization of 3D data.
Displays multiphase CT and MRI data in cine mode, synchronizing 2D cross-sectional images and 3D reconstruction images.
Calculates apparent diffusion coefficients (ADC) from MRI diffusion-weighted (DWI) images, allowing detailed analysis of ADC and eADC in specific regions.
It unites multiple series of images into a single continuous view, making it easy to study large areas.
It generates panoramic and cross-sectional images of teeth and alveolar bones from CT images, aiding in the planning of dental implants.
Evaluates temporal changes in MRI and PT images, displaying images of individual parameters and time intensity curves in multiphase analyses, allowing for more detailed clinical evaluation.
Calculates areas and volumes of subcutaneous and visceral fat in multiple planes (3D*). With automatic extraction of the psoas muscle, allowing an analysis of volumes.
*3D solution is optional
It allows the fusion of anatomical and functional data from two different modalities such as PET-CT, PET-MR and SPECT-CT or images of the same modality with different exposure times.
Designed to create curved planar reformatted (CPR) imaging for blood vessel analysis, such as stenosis measurements, stent graft planning, and calcification analysis.
It produces orthogonal or oblique reconstructions in 2D images, with direct integration to the '3D Viewer' for further analysis.
It simulates ultrasound exams especially for biopsy and aspiration planning, ideal for the visualization of probe insertions and censis.
Reconstructs data from the spine at multiple angles, aiding in complex analyses such as scoliosis assessment.
Creates STL files for 3D printing and interactive PDFs for reports and presentations.
Offers calculations extracted from MRI signal values. The clinical utility of T2 assessment includes cartilage and collagen analysis to determine iron deposits and distribution.
Calculates and displays the volume, velocity, and vector of blood flow in specific regions, presenting the results in time intensity curve graphs
It creates virtual mono images from CT series taken with different kV. It also enables material decomposition analysis and the creation of virtual images without contrast, optimizing advanced diagnostics.
Offers specialized tools for interventional planning, including liver segmentation for embolization.
Performs automatic segmentations of bones, menisci, and knee cartilage for detailed analysis.
Automatically extracts and labels the spine and ribs, displaying the results in 3D images and CPR (planar curve reformatting).
- 1. Kirişli HA, et al., Standardized evaluation framework for evaluating coronary artery stenosis detection, stenosis quantification and lumen segmentation algorithms in computed tomography angiography, Medical Image Analysis, 2013.
- 2. Lo P, van Ginneken B, Reinhardt JM, Tarunashree Y, de Jong PA, Irving B, Fetita C, Ortner M, Pinho R, Sijbers J, Feuerstein M, Fabijanska A, Bauer C, Beichel R, Mendoza CS, Wiemker R, Lee J, Reeves AP, Born S, Weinheimer O, van Rikxoort EM, Tschirren J, Mori K, Odry B, Naidich DP, Hartmann IJ, Hoffman EA, Prokop M, Pedersen JH, de Bruijne M. "Extraction of Airways from CT (EXACT’09)", in IEEE Transactions on Medical Imaging. 2012;31:2093-2107.
- 3. Komai Y, Sakai Y, Gotohda N, Kobayashi T, Kawakami S, Saito N. A novel 3-dimensional image analysis system for case-specific kidney anatomy and surgical simulation to facilitate clampless partial nephrectomy. Urology. 2014;83(2):500-7.
- 4. Abe Y, Itano O, Kitago M, Shinoda M, Yagi H, Hibi T, Takano K, Chiba N, Kawachi S, Shimazu M, Kitagawa Y. Computer assisted surgery, preoperative planning, and navigation for pancreatic cancer. Journal of Hepatobiliary Pancreatic Sciences. 2014;21(4):251-5.