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Fusion of “Diagnosis” with “Treatment”
to deliver required drugs with appropriate dose to target site effectively
With improvement in living environment and the level of medical care, and populations aging worldwide in recent years, increased cases of cancer and cognitive impairment have become social serious issues.
Infection diseases are also expanding due to increasing movement of people globally and multiple types of drug-resistant bacteria.
It has been being revealed that many of those diseases have complex mechanisms to make pathology and progression different in relevant patients and are thus difficult to be effectively treated via standard of medical care.
As a total healthcare company, Fujifilm tries to address these issues with a unique approach that combines various technologies such as chemistry, biology, imaging, and artificial intelligence (AI) and thereby fusion of “diagnosis” with “treatment.”
Fujifilm also aims to realize medical care that truly improves patient quality of life (QOL) by establishing mechanisms that “to deliver required drugs with appropriate dose to target site effectively” through target-based drug discovery and development of drug delivery system (DDS) as well.
This will simultaneously provide various effects including improved burden of medical costs resulting from the improvement of drug safety and the reduction of unnecessary drug treatment.
In addition to the current contract manufacturing of antibacterial agents such as penicillin, we are promoting a contract manufacturing business by utilizing the manufacturing infrastructure of pharmaceutical products that started operation in 2021 for lipid nanoparticles (LNPs), which is one of the drug delivery system technologies.
We will expand the contract manufacturing business to next-generation pharmaceuticals such as mRNA and nucleic acid therapies, aiming for continuous growth of our business.
Conventional Standard Medical Treatment
Pharmaceutical Business of Fujifilm Group
Examples of Fusion of “Diagnosis” with “Treatment”
(1) Drug Development for Alzheimer's Disease Based on a Combination of Diagnostic Agents and AI
In drug development of Alzheimer's disease, an important approach is to improve success rate of clinical trials by accurately understanding individual disease conditions and checking individual administration of appropriate drugs. Fujifilm develops AI technology that predicts the progression of Alzheimer's disease through combining unique imaging technologies to analyze brain images and measure atrophy rates of respective regions in brain, with a database of multimodal health information. We are trying to improve the quality of clinical trials, and thereby promote success of drug development for Alzheimer's disease through the combination of diagnostic agents and AI.
(2) Administration of an Antibacterial Agent Specific to a Bacterial Strain Identified with In Vitro Diagnosis
In recent years, frequent uses of broad-spectrum antibacterial agents have have caused a worldwide problem due to the development of bacteria and viruses with antimicrobial resistance (AMR) worldwide. Fujifilm seeks to realize target-based therapy to ensure treatment with antibacterial agents specific to bacterial strains in infected patients that are precisely identified with in vitro diagnostic systems of the Fujifilm Group. Fujifilm aims to improve effectiveness of treatment, and restrict the spread of AMR resulting from attack on non-target bacterial strains.
(3) Process development and contract manufacturing of liposomes and lipid nanoparticles (LNPs) leveraging Fujifilm’s drug delivery system technologies
We provide seamless services of formulation design, production process development, and manufacturing for liposomes and LNPs to meet customer requests from basic research to commercial manufacturing.
Utilizing cutting edge nano-dispersion, analysis, and synthesis technologies that have been cultivated and evolved through the development of a wide range of Fujifilm’s products such as photographic film, we provide optimal liposomes and LNPs that meet customer needs.
Provides clinical reagents (in vitro diagnostics).